Overview:

Botox, also known as onabotulinumtoxin, is an injectable medicine that has been approved by the US Food and Drug Administration (FDA) for the preventive treatment of refractory migraines in adults. The Botox molecule is taken up by local nerve endings where it temporarily prevents release of specific molecules (acetylcholine), thereby reducing muscle spasms and pain. Botox has been demonstrated effective in reducing headache frequency. The medication is injected into specific muscles, usually around the forehead, temples, and neck, every 12 weeks.

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