Knee injections are used for a variety of conditions that cause knee pain or inflammation, including osteoarthritis, rheumatoid arthritis, gout, bursitis, tendonitis and knee joint pain due to injury or trauma, such as a knee sprain or strain. The specific type of knee injection used and the frequency of injections will depend on the individual patient and the specific condition being treated. Knee injections can provide pain relief, reduce swelling and improve mobility. Knee injections are quick, minimally invasive, convenient, and may help delay or avoid the need for knee surgery.