Vulvovaginal pain or vulvodynia is discomfort in the vulva or female genital area that can affect the skin, labia, clitoris, and the opening of the vagina. The cause is uncertain, but it could be due to irritation or injury to the nerves or to an infection (vaginitis) such as candida. Women are more likely to be affected by vaginitis if they are taking antibiotics, are pregnant, or have an illness in which the immune system is debilitated. Other causes of vaginal pain may include injury or trauma, hormonal changes, muscle spasms or weakness of the pelvic floor. Associated symptoms may include itching, burning, soreness, stinging or bleeding, pain during intercourse or urination, and vaginal dryness. If vaginal pain occurs, it is important to seek medical attention to receive appropriate treatment and avoid long-term damage to the reproductive system.