Targeted Anti-Inflammatory Injections for Joint, Spine, and Nerve Pain

Cortisone shots are anti-inflammatory injections used to relieve pain caused
by irritated joints, inflamed soft tissue, or compressed nerves.

At UES Interventional Pain, Matthew Spiegel, MD uses
cortisone injections selectively and precisely—often with imaging
guidance—to treat pain affecting the spine, major joints, and surrounding
soft tissues.

Cortisone injections are not a cure. When used appropriately, however, they
can significantly reduce inflammation, improve mobility, and create a window
for healing or rehabilitation.

What Is a Cortisone Shot?

A cortisone shot is an injection of a corticosteroid medication, often
combined with a local anesthetic, delivered directly to the source of
inflammation. Unlike oral anti-inflammatory medications, cortisone works
locally, targeting inflamed tissue while minimizing whole-body exposure.

These injections are commonly used in interventional pain management to
reduce swelling, relieve pressure on irritated nerves, and improve function.

What Conditions Can Cortisone Shots Treat?

Cortisone injections are used to treat inflammatory pain in the
spine, joints, and soft tissues, depending on the
underlying cause.

In spinal conditions, cortisone may help reduce inflammation around
irritated nerves that contribute to back pain, neck pain, or radiating nerve
symptoms. In joints, it is often used to ease pain and stiffness related to
arthritis or joint irritation. In soft tissues, cortisone can calm
inflammation affecting bursae or tendons.

Because each condition behaves differently, proper evaluation is essential
to determine whether cortisone is the right treatment—and where it should be
placed.

How Cortisone Shots Work

Corticosteroids are powerful anti-inflammatory medications. When injected
near the source of pain, cortisone works by:

• Reducing inflammation and swelling
• Decreasing pressure on irritated nerves
• Improving joint mobility
• Interrupting pain signaling

Some patients notice improvement within a few days, while others experience
gradual relief over the course of a week.

How Long Does Relief Last?

Cortisone shots provide temporary or lasting relief. The
duration varies.

Relief may last weeks to several months or longer Some patients experience
shorter or longer benefit Results are often improved when injections are
combined with physical therapy or guided rehabilitation Because cortisone does
not repair structural damage, it is typically used as part of a broader
treatment strategy rather than as a standalone solution.

Are Cortisone Shots Painful?

Most patients tolerate cortisone injections well.

• A brief pinch or pressure may be felt during the injection
• Local anesthetic is commonly used
• Mild soreness afterward is normal

Some patients experience a short-lived increase in pain—known as a
cortisone flare — before improvement begins.

Side Effects & Safety Considerations

When used appropriately and sparingly, cortisone injections are generally
safe. Possible short-term side effects include:

• Temporary soreness or swelling
• Facial flushing
• Headache
• Difficulty sleeping
• Temporary elevation in blood sugar

Risks of Repeated Use

Frequent injections in the same area may increase the risk of:

• Cartilage damage
• Tendon weakening
• Bone density loss
• Skin thinning at the injection site

For this reason, cortisone injections are typically spaced several months
apart and used judiciously.

Who Should Avoid Cortisone Shots?

Cortisone injections may not be appropriate for patients with:

• Active infection
• Certain bleeding disorders or anticoagulant use
• Poorly controlled diabetes
• Specific tendon injuries where weakening could increase risk

A thorough medical evaluation helps ensure the treatment is both safe and
appropriate.

Cortisone Shots vs. Other Injection Options

Cortisone is one of several tools used in interventional pain management.
Depending on the cause of pain, other treatments may be more effective,
including nerve blocks, epidural injections, trigger point injections, or
radiofrequency procedures.

Choosing the right approach depends on accurate diagnosis—not just symptom
location.

Same-Day Injections & Care Quality

Many patients search for same-day or walk-in cortisone shots. While
convenience is appealing, precise diagnosis and proper placement are
critical for safety and effectiveness.

At UES Interventional Pain, injections are performed only after evaluation
and are tailored to the patient’s specific condition, anatomy, and goals of
care.

Cost & Insurance Considerations

The cost of a cortisone injection depends on the type of injection, use of
imaging guidance, and insurance coverage. Our office can review benefits and
discuss expected costs before treatment.

Is a Cortisone Shot Right for You?

Cortisone injections can be an effective way to reduce inflammation and
pain—but only when used for the right condition, in the right location, and
at the right time.

If you are experiencing persistent joint pain, spine-related pain, or nerve
symptoms, an evaluation with an interventional pain specialist can help
determine whether cortisone—or another treatment—is the best option.