Injection and Shot - Matthew A. Spiegel, MD

Injections & Nerve Blocks: Targeted Pain Relief Without Surgery

Dr. Matthew Spiegel offers a full range of minimally invasive, image-guided injections and nerve blocks to reduce inflammation, calm irritated nerves, and get you back to daily life. Here's what each one does and where to learn more.

Epidural Steroid Injection (ESI)

An epidural steroid injection delivers anti-inflammatory medication directly around irritated spinal nerves to calm sciatica, herniated disc, and spinal stenosis pain, often creating a lasting window of relief without surgery.

Learn MORE

Joint Injections

A joint injection places medication directly into a painful joint—such as the knee, hip, shoulder, or another affected joint—to reduce inflammation, relieve pain, and improve movement.

Learn MORE

Cortisone (Steroid) Injection

A cortisone injection delivers a corticosteroid straight to an inflamed joint, tendon, or bursa — an arthritic knee, hip, or shoulder, or a case of bursitis — for fast, targeted relief.

Learn MORE

Trigger Point Injections

Trigger point injections release tight, painful knots of muscle — often in the neck, shoulders, or lower back — with a small dose of anesthetic to break the pain-spasm cycle and restore range of motion.

Learn MORE

Sacroiliac (SI) Joint Injection

An SI joint injection places numbing medication and steroid into the joint where the spine meets the pelvis, both confirming the SI joint as the pain source and reducing the inflammation behind buttock, hip and lower back pain.

Learn MORE

Facet Joint Injection

A facet joint injection places anesthetic and steroid into the small stabilizing joints along the spine to ease arthritis-related neck or back pain and confirm whether those joints are the true source.

Learn MORE

Medial Branch Block (MBB)

A medial branch block numbs the small nerves carrying pain signals from arthritic facet joints, relieving chronic neck or back pain while helping determine if a longer-lasting radiofrequency ablation would help.

Learn MORE

Radiofrequency Ablation (RFA)

RFA uses a heated electrical current to disable the nerves causing facet or SI joint pain, offering longer-lasting relief — typically 6-18 months or longer — than a standard injection.

Learn MORE

Hyaluronic Acid (Viscosupplementation / Gel) Injection

Also called a gel shot, this injection lubricates an arthritic knee, hip, or shoulder joint to ease pain and improve movement, often as an alternative to steroid injections.

Learn MORE

Genicular Nerve Block

This injection targets the sensory nerves supplying the knee joint to reduce chronic knee pain, and can help identify candidates for a longer-lasting genicular radiofrequency ablation.

Learn MORE

Peripheral Nerve Block

A peripheral nerve block delivers anesthetic or steroid directly to a specific irritated nerve, such as in carpal tunnel syndrome or another localized nerve injury, to interrupt pain signals and pinpoint their source.

Learn MORE

Coccyx (Tailbone) Injection

A coccyx injection places local anesthetic, often with steroid, around the tailbone or sacrococcygeal joint to help diagnose and relieve persistent tailbone pain (coccydynia), particularly when sitting is painful.

Learn MORE

Intercostal Nerve Blocks

An intercostal nerve block delivers local anesthetic, often with steroid, near one or more nerves running beneath the ribs to help relieve chest-wall or rib pain from conditions such as intercostal neuralgia, shingles, or a rib injury.

Learn MORE

Sympathetic Nerve Blocks

A sympathetic nerve block places local anesthetic near sympathetic nerves along the spine to interrupt pain signals and help diagnose or treat sympathetically mediated pain, including complex regional pain syndrome (CRPS) or vascular-type pain affecting an arm or leg.

Learn MORE

Pudendal Nerve Block

A pudendal nerve block places local anesthetic, sometimes with steroid, near the pudendal nerve to help diagnose and relieve pain arising from this nerve in the pelvic and perineal region.

Learn MORE

Kyphoplasty, Vertebroplasty & Sacroplasty (Cement Injection)

For a painful spinal or sacral compression fracture, these procedures inject medical grade bone cement into the fractured vertebra to stabilize it and relieve pain; kyphoplasty also uses a balloon first to help restore height.

Learn MORE

Basivertebral Nerve Ablation (BVNA or Intracept®)

The BVNA procedure ablates the nerve inside the vertebra itself to treat chronic low back pain coming from damaged vertebral endplates or neighboring degenerated discs, with relief that can last for years since the nerve doesn't regenerate.

Learn MORE

Every injection is performed by Dr. Spiegel using image guidance for precision and safety. Book a same-day evaluation.

Surgery is not your only option. But if it ever becomes the right one, you won't face it alone.

Frequently Asked Questions

Why Choose UES Interventional Pain?

When you’re in pain, you need more than a quick prescription or a rushed five-minute visit. At UES Interventional Pain, we combine medical expertise with a patient-first approach so you feel heard, understood, and confident in your care.

Board-Certified Expertise – Our physicians are trained in the most advanced interventional pain techniques, so you get precise, targeted treatment.
Local Care, Global Standards – We’re right here in the Upper East Side, serving patients from across Manhattan and beyond, but we hold ourselves to the highest international standards of safety and outcomes.
Tailored Treatment Plans – No one-size-fits-all care. Every plan is built around your condition, lifestyle, and goals.
Access and Convenience – Same-day and next-day appointments, easy subway access, and nearby parking options make getting care stress-free.

Whether you need a simple injection or a minimally invasive procedure, we guide you through every step with the goal of not just easing your pain, but helping you move freely and confidently again.

Do you offer same-day appointments?

Yes. We reserve slots for urgent cases so you can get relief as quickly as possible.

Where are you located in the Upper East Side?

Our office is located at 215 E 77th Street, between 2nd and 3rd Avenue, near the 6 and Q trains.

Is there parking nearby?

Yes. Nearby options include CitiParking at 77th and 3rd, Lenox Parking at 77th and 2nd, and Icon Parking at 75th and 2nd.

Google Reviews

“Glad I found Dr. Spiegel”

Offers treatment possibilities that have not been explored by other doctors I’ve consulted and been treated by. The staff is exceptional. Caring, patient. I recommend the good doctor and his aides and staff.

“I truly believe this doctor cares deeply about his patients.”

His team is incredible, which speaks volumes about the quality of care and his representation in this world. He has helped me improve my health, and I feel fortunate to have met him in a city filled with millions of doctors.

“Dr. Spiegel is exceptional in diagnosis and treatment”

He is thorough, efficient, caring and effective. His office staff is quite literally the kindest, most professionally managed group I’ve encountered in NYC. I highly recommend.

“Dr. Spiegel is a lifesaver!”

He really took the time to listen and got me back on track fast. Super friendly staff, and the whole process was a breeze. I’m finally feeling relief, and I couldn’t be happier. Highly recommended if you’re looking for real results.

“Dr. Spiegel provided fantastic and personal care”

After a long and arduous journey searching for relief Dr. Speigel helped me regain my life. I am forever thankful for Dr. Speigel’s personal care and excellent bedside manner. He had great bed side manner as well.

“Caring, compassionate and helpful”

He listened carefully and was responsive to any questions that I had. His staff were also extremely helpful and kind.

“This man saved my life”

After 30 years of suffering the worst neck pain anyone can endure and having multiple surgery this man fixed it with on simple injection to my neck! I wasn't planing on continuing my life like this this man saved my life!

“Dr. Spiegel was phenomenal”

Dr. Spiegel was phenomenal! He asked a lot of questions about the pain I was feeling, he performed some tests, and seamlessly was able to schedule an MRI and cortisone shots for my back. Would highly recommend.

Shots & Injections for Pain Relief

Epidural Steroid Injection (ESI)

Joint Injections

Cortisone (Steroid) Injection

Trigger Point Injections

Sacroiliac (SI) Joint Injection

Facet Joint Injection

Medial Branch Block (MBB)

Radiofrequency Ablation (RFA)

Hyaluronic Acid (Viscosupplementation / Gel) Injection

Genicular Nerve Block

Peripheral Nerve Block

Coccyx (Tailbone) Injection

Intercostal Nerve Blocks

Sympathetic Nerve Blocks

Pudendal Nerve Block

Kyphoplasty, Vertebroplasty & Sacroplasty (Cement Injection)

Basivertebral Nerve Ablation (BVNA or Intracept®)

With a proven record of success, Dr. Spiegel delivers expert care that leads to lasting relief for patients.

NYU Grossman
Pediatric Narrative
Award

Hofstra/Northwell
Teaching Associate
Award

Ivy League
Excellence

Double
Board-Certified

Phi Beta Kappa Honors

Official Medical Partner
of NYS Troopers PBA

NYU Scholar Award

Abstract Award

Matthew A. Spiegel, MD

Shots & Injections for Pain Relief

Injections & Nerve Blocks: Targeted Pain Relief Without Surgery

Epidural Steroid Injection (ESI)

Joint Injections

Cortisone (Steroid) Injection

Trigger Point Injections

Sacroiliac (SI) Joint Injection

Facet Joint Injection

Medial Branch Block (MBB)

Radiofrequency Ablation (RFA)

Hyaluronic Acid (Viscosupplementation / Gel) Injection

Genicular Nerve Block

Peripheral Nerve Block

Coccyx (Tailbone) Injection

Intercostal Nerve Blocks

Sympathetic Nerve Blocks

Pudendal Nerve Block

Kyphoplasty, Vertebroplasty & Sacroplasty (Cement Injection)

Basivertebral Nerve Ablation (BVNA or Intracept®)

With a proven record of success, Dr. Spiegel delivers expert care that leads to lasting relief for patients.

NYU GrossmanPediatric NarrativeAward

Hofstra/NorthwellTeaching AssociateAward

Ivy LeagueExcellence

DoubleBoard-Certified

Phi Beta Kappa Honors

Official Medical Partnerof NYS Troopers PBA

NYU Scholar Award

Abstract Award

Matthew A. Spiegel, MD

Reviews & Testimonials

Where To Find Us

Upper East Side

Frequently Asked Questions

NYU Grossman
Pediatric Narrative
Award

Hofstra/Northwell
Teaching Associate
Award

Ivy League
Excellence

Double
Board-Certified

Official Medical Partner
of NYS Troopers PBA