The mandibular nerve is one of the branches of the trigeminal nerve and provides sensation to the lower part of the face and jaw. It also provides motor innervation to the muscles of mastication, which are responsible for biting and chewing. For patients suffering from lower facial pain a mandibular nerve block may provide relief. These conditions commonly include trigeminal neuralgia or chronic dental pains. Local anesthetic plus steroid is typically injected at the site of the mandibular nerve under fluoroscopic guidance. The procedure is done as an outpatient procedure, is considered safe and with a low risk of complications. Many times, the maxillary and mandibular nerves are blocked together.